Silver Sulfadiazine
Silver sulfadiazine is a topical antimicrobial drug indicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns. It has broad antimicrobial activity against many Gram-negative and Gram-positive bacteria, as well as yeast.
Dosage by Body Weight
Apply to cleansed and debrided burn wounds once to twice daily to a thickness of approximately 1.5 mm (1/16 inch). The burn areas should be covered with the cream at all times. Reapply immediately if the cream is rubbed off.
- Body Weight
- Below 5 kg
- Dose
- Topical application (1.5 mm thickness)
- Frequency
- 1-2 times daily
- Tracking Notes
- Contraindicated in premature infants and newborns under 2 months of age due to the risk of kernicterus.
- Body Weight
- 5-7 kg
- Dose
- Topical application (1.5 mm thickness)
- Frequency
- 1-2 times daily
- Tracking Notes
- Contraindicated if infant is less than 2 months old. Use with caution over large surface areas to avoid systemic absorption.
- Body Weight
- 8-10 kg
- Dose
- Topical application (1.5 mm thickness)
- Frequency
- 1-2 times daily
- Tracking Notes
- For topical use only. Maintain continuous coverage of the wound.
- Body Weight
- 11-15 kg
- Dose
- Topical application (1.5 mm thickness)
- Frequency
- 1-2 times daily
- Tracking Notes
- For topical use only. Reapply if cream is displaced by patient movement or dressing changes.
- Body Weight
- 16-20 kg
- Dose
- Topical application (1.5 mm thickness)
- Frequency
- 1-2 times daily
- Tracking Notes
- For topical use only. Ensure the wound remains fully covered between dressing changes.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Topical application (1.5 mm thickness) | 1-2 times daily | Contraindicated in premature infants and newborns under 2 months of age due to the risk of kernicterus. |
| 5-7 kg | Topical application (1.5 mm thickness) | 1-2 times daily | Contraindicated if infant is less than 2 months old. Use with caution over large surface areas to avoid systemic absorption. |
| 8-10 kg | Topical application (1.5 mm thickness) | 1-2 times daily | For topical use only. Maintain continuous coverage of the wound. |
| 11-15 kg | Topical application (1.5 mm thickness) | 1-2 times daily | For topical use only. Reapply if cream is displaced by patient movement or dressing changes. |
| 16-20 kg | Topical application (1.5 mm thickness) | 1-2 times daily | For topical use only. Ensure the wound remains fully covered between dressing changes. |
Formulation
Purpose
Prevention and treatment of wound sepsis in patients with second- and third-degree burns.
Generic Name
Silver SulfadiazineBranded Drug Names
Silver Sulfadiazine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.